There are five new cases of COVID-19 in Kasabonika Lake First Nation.
The Sioux Lookout First Nations Health Authority were notified Tuesday of one positive case in the remote community.
Officials say there are now four other cases, all within the family of the original individual.
All of those infected are said to be doing well and are in self-isolation.
The Health Authority is working with local health staff to support those impacted and the entire First Nation.
Ontario is reporting 293 new cases of the coronavirus Thursday, bringing the provincial total to 45,676.
The case count is a slight decrease from Wednesday which saw 315 new cases but is higher than Tuesday, which saw 251 cases.
According to the report, 85 new cases were recorded in Toronto, 63 in Peel Region, 39 in Ottawa, 37 in York Region and 12 in Halton Region.